While this seems to be no Zope specific question,
as we all know how to narrow down the test selection with pytest (e.g. pytest -k pattern),
Zope does not use pytest, but zope.testrunner.
Similar to pytest,
also zope.testrunner offers some command line options,
see https://zopetestrunner.readthedocs.io/en/latest/getting-started.html#some-useful-command-line-options-to-get-you-started
This means,
in order to run a specific test, you can use the -t flag,
which takes one or more regex expressions as input, e.g. -t some_test.
When developing against Zope, you can use tox.
Via -- it is possible to inject extra arguments into the command run by tox,
see https://tox.readthedocs.io/en/latest/example/general.html
e.g. tox -e py38 -- -t some_test